Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent patients
نویسندگان
چکیده
منابع مشابه
Medial orbitofrontal cortex gray matter is reduced in abstinent substance-dependent individuals.
BACKGROUND Chronic exposure to drugs of addiction induces cellular adaptations in orbitofrontal cortex (OFC) and associated limbic-prefrontal pathways that might underlie abuse-related behavior. A propensity to make risky decisions in spite of substantial negative consequences might be mediated by medial OFC dysfunction in substance-dependent individuals (SDI). We tested the hypothesis that med...
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ژورنال
عنوان ژورنال: Drug and Alcohol Dependence
سال: 2008
ISSN: 0376-8716
DOI: 10.1016/j.drugalcdep.2007.12.014